（《临床心血管病杂志》 2003年 第19卷 第11期）
袁义强 刘怀霖
摘要 目的：探讨血管紧张素转化酶抑制剂（ACEI）对器质性心脏病合并阵发性心房颤动（AF）P波离散度（Pd）、最大P波时限（Pmax）及AF发生率的影响。方法：59例器质性心脏病合并AF患者，随机分成两组：实验组，为30人；对照组：为29人。实验组给予卡托普利干预，观察卡托普利对P波离散度（Pd）、最大P波时限（Pmax）及AF发生率的影响。结果：实验组3个月后
Pd、Pmax明显减小，AF的发生率较对照组亦明显降低。结论：ACEI可减小Pd、Pmax，同时部分预防AF的发生。
关键词 心房颤动 血管紧张素转化酶抑制剂 心电图 P波离散
Abstract Objective: To investigate the influence of angiotensin coverting enzyme inhibitor on P dispersion(Pd), maximal time of P waves(Pmax) and recurrence rate of atrial fibrillation(AF).Method:59 patients, who had organic heart diseases combined with AF, were divided into two groups at random: the experiment group included 30 patients; the contrast group included 29 patients. The patients from experiment group toke catopril, and observed the influence of catopril on Pd,Pmax and recurrence of AF. Result: After 3 months The Pd and Pmax decreased, and the recurrence rate of AF obviously decreased compared with the contrast group too. Conclusion: ACEI can dicrease Pd and Pmax, and at the same time can prevent the recurrence of AF.
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Key words Atrial fibrillation; Angiotensin coverting enzyme inhibitor; Electrocardiogram; P dispersion
随着心房颤动（AF）成为心脏电生理研究领域的一个热点，近期对其发生的预测指标亦进行了较多探讨。有报道AF患者的P波最大时限（Pmax）和P波离散度（Pd）较窦性心律增大[1]。血管紧张素转化酶抑制剂（ACEI）能够减轻心房电重构，减少复律后AF的发生，但ACEI对Pd和Pmax是否有影响呢？目前尚缺乏研究，本文主要做一点这方面的研究。
1 资料与方法
1.1
临床资料
来自我院住院和/或门诊病人59例，男35例，女2 [1] [2] [3] [4] 下一页 |
